Profhilo London your skin, renewed.

An advanced skin remodelling treatment. Not a filler.

Not a moisturiser. A biological approach to supporting your skin — improving quality, elasticity and glow from within. Administered personally by Dr Gregorio De Carvalho at Vitalumina’s Kensington clinic.

What is Profhilo?

Profhilo is an injectable skin remodelling treatment made by IBSA and containing one of the highest concentrations of hyaluronic acid of any injectable product — 64mg in just 2ml. It is unlike anything else available in aesthetic medicine.

The key difference: Profhilo does not fill or add volume. Once injected at five specific anatomical points on each side of the face, it spreads extensively beneath the skin — stimulating the production of collagen and elastin and profoundly improving tissue quality, hydration and laxity over the following weeks.

The result is not a structural change. It is a quality change. Your skin simply looks better — more hydrated, more elastic, more luminous. People notice, but they cannot say why.

Profhilo versus other skin boosters

Profhilo belongs to the category of injectable skin boosters, with a distinct mechanism of action. Traditional skin boosters like Juvederm Volite and Restylane Skinboosters hydrate and improve skin quality effectively. Profhilo contains a patented formulation of both high and low molecular weight hyaluronic acid that spreads far more extensively beneath the skin, stimulating a broader bioremodelling response. Think of it as the difference between watering a plant and changing its soil.

Where the concern is overall skin quality rather than hydration alone, Rejuran treatment in London may also be discussed at consultation. Dr Gregorio will advise which approach is more appropriate for your skin.

TREATMENT OVERVIEW

Treatment price From £360
Treatment time 30–60 minutes
Downtime Minimal – none
Results visible Immediately
Duration of results 9–18 months
Anaesthetic Topical + in-product
Product type Hyaluronic acid (HA)
Reversible Yes — dissolve with hyaluronidase

What our patients say.

★★★★★

Dr. José Gregorio is truly exceptional. I trust him with my face like no one else, and that says it all. His expertise, precision, and aesthetic eye are outstanding. Every procedure leaves me looking refreshed, natural, and confident.

music art company

★★★★★

Dr. José Gregorio is truly exceptional. I trust him completely with my face. His skill, precision, and strong aesthetic eye are outstanding. The results are always natural, balanced, and never overdone.

Angelica Lopez Official

★★★★★

Dr. Gregorio is a highly qualified professional with an excellent eye for achieving natural aesthetic results. He is experienced and offers a full range of aesthetic treatments, including advanced facial rejuvenation options.

G A

★★★★★

I had an excellent skincare consultation and treatment with Dr. Gregorio. He was thorough, attentive, and took the time to tailor the treatment to my skin’s needs. I felt very well looked after from start to finish and noticed a clear improvement.

Ian Johnson

★★★★★

An excellent experience from start to finish. From the very beginning, the staff were kind and professional, always attentive to every detail. The facilities are spotless, modern, and inspire complete confidence.

Roimar De Carvalho

★★★★★

I had an amazing experience with Dr. Gregorio for both Botox and fillers. From the moment I arrived, he made me feel completely comfortable. The whole process was painless, which really surprised me, and the results looked natural and elegant.

Mark Johnson

★★★★★

I had several procedures done with Dr. Gregorio and I loved the results. His work is very professional and successful. Based on my own experience, I highly recommend him.

Lizete Ferriera

★★★★★

I have had the opportunity to use Dr. Gregorio’s services and he is truly very professional in his work. He always meets my expectations and helps me feel my best.

Martha Toro

★★★★★

I recently had a shoulder contour treatment with Botox, together with an upper facial rejuvenation technique performed by Dr. Gregorio. The results are outstanding. My skin looks smooth, firm, defined, and completely natural.

Tianyuan Wang

★★★★★

Dr. Greg is the best in London. He has done my fillers and Botox and he is truly the best. His work is so natural that nobody will notice what I have had done. He always knows exactly how to enhance my features beautifully.

Isabelle Wong

★★★★★

A very competent doctor with extensive experience. I highly recommend him for his excellent clinical results.

Stella Stefanova

★★★★★

I have known Dr. Gregorio for more than 10 years and I have always been very satisfied with the results of every procedure he has performed on me. His work is consistently professional, thoughtful, and reliable.

Catalina Drane

★★★★★

I loved Dr. Gregório’s work and highly recommend him.

Lauriane Ferreira

★★★★★

The best doctor in Ontario!

Alexander Zerpa

★★★★★

Five-star experience.

Fátima Patricia Araujo Silva

★★★★★

I have been a patient of Dr. Gregorio for more than 10 years and I can confidently say my experience has been exceptional. From the first appointment, he made me feel comfortable and valued, always taking the time to understand my needs.

Lucianne Sythes

★★★★★

Excellent experience.

Ingrid

★★★★★

Excellent experience.

Maria Gil

What skin concerns does Profhilo treat?

Profhilo is not for everyone — it is specifically effective for skin quality concerns rather than structural or volume issues. These are the conditions it addresses best.

Skin Laxity

01
Mild to moderate skin looseness — particularly along the jawline, neck and cheeks — responds well to Profhilo as collagen and elastin production is stimulated. Where laxity is more pronounced, a thread lift may be discussed as an alternative approach at consultation.

Dehydrated Skin

02
Skin that feels tight, looks dull or shows fine dehydration lines benefits immediately from the intense hydration delivered by Profhilo’s high HA concentration.

Crepey Skin Texture

03
Thin, crepey skin — particularly on the neck, décolletage and hands — shows significant improvement in texture and elasticity after a full Profhilo course. Where the neck and jaw contour is the main concern, a neck and jawline lift may also be considered.

Early Signs of Ageing

04
Fine lines from dehydration and early loss of skin firmness respond well. Profhilo is ideal as a preventative treatment for patients in their late 30s and 40s.

Dull, Tired Complexion

05
The bioremodelling effect of Profhilo produces a visible improvement in skin luminosity and tone — the glow patients describe as looking naturally refreshed.

Post-Summer Skin Damage

06
Sun exposure accelerates skin ageing and depletes hyaluronic acid. A Profhilo course in autumn is a highly effective way to restore skin quality after summer.

How many Profhilo sessions do I need?

Profhilo works on a specific two-session protocol. This is not a single injection — it is a structured course designed to progressively stimulate tissue remodelling.
01

First Treatment

Profhilo is injected at 5 BAP points per side of the face — 10 injection points in total. Each session takes approximately 20–30 minutes. Small bumps at injection sites are normal and resolve within a few hours. The product begins spreading beneath the skin immediately.
02

Second Treatment

The second session reinforces and amplifies the remodelling process begun by the first. By this point many patients already notice improved skin texture and hydration. The full effect of both sessions becomes visible 4–6 weeks after the second treatment as collagen and elastin production peaks.
03

Maintenance : Every 6 Months

To maintain optimal results, a single maintenance session every 6 months is recommended. Patients who continue with regular Profhilo treatments often find the cumulative benefit on skin quality and tissue health increases over time — with each course building on the foundation of the last.

Frequently asked questions about Profhilo in London.

Profhilo is an injectable skin remodelling treatment containing 64mg of hyaluronic acid — one of the highest concentrations available. Unlike fillers, it does not add volume. It spreads beneath the skin and stimulates the production of collagen and elastin, improving overall skin quality, hydration, elasticity and glow from within.
The standard protocol is two sessions, four weeks apart. Most patients notice initial improvement after the first session, with full results visible 4–6 weeks after the second treatment. Maintenance sessions every six months are then recommended to sustain and build on the results.
They are completely different treatments. Dermal fillers add volume and structure to specific areas of the face — cheeks, jawline, lips. Profhilo adds no volume at all. It improves the quality of the skin itself by stimulating collagen and elastin production. Fillers address structural changes. Profhilo addresses skin quality. Many patients benefit from both.
Results from a full two-session course typically last approximately six months. A maintenance session every six months sustains and builds on the results. Patients who continue regularly often find the cumulative benefit on skin quality increases with each course.
Profhilo is well-tolerated by most patients. The BAP technique uses only 10 injection points across the entire face, which keeps discomfort minimal. Topical numbing cream can be applied beforehand if requested. Small bumps appear at injection sites immediately after treatment and typically resolve within a few hours.
Profhilo is suitable for adults who want to improve overall skin quality rather than add volume. It is particularly effective for skin laxity, dehydration, dullness, crepey texture and early ageing. It works well as a standalone treatment or alongside dermal fillers and other procedures for comprehensive rejuvenation.